Efficacy and safety analysis of gastrodin injection combined with anti-anxiety drug for treatment of climacteric hypertension

Objective: This study aimed to analyze the effect of gastrodin injection combined with anti-anxiety drugs on climacteric hypertension. Methods: 106 cases menopausal hypertensive patients who were treated in our hospital between September 2013 and September 2014 were enrolled in the study. They were randomly divided into two groups and treated with routine therapy and gastrodin injection combined with anti-anxiety drugs, respectively. After the treatment, baseline data of the study, clinical efficacy, mental status, safety and other data were compared between the two groups. Results: In observation group and the control group total effective rate of hypertension were 85.2% and 61.5%. Comparisons between the two groups showed that in the observation group it was significantly better than the control group (P < 0.05). After treatment HAMD score were (14.3 ± 3.6) points and (17.6 ± 3.5) points. In the observation group it was significantly lower than that in the control group (P < 0.05). Total efficiency rate of anxiety were 83.3% and 9.6%. Comparisons between the two groups showed that in the observation group it was significantly better than that in the control group (P < 0.05); adverse reaction rate were 14.8% and 26.9%. In the observation group it had a significant advantage (P < 0.05). That is, for the safety of the two therapies, in observation group it was significantly better than the control group (P < 0.05). Conclusion: Gastrodin injection combined with anti-anxiety drugs is safe and effective for the treatment of menopausal hypertensive.